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Difference Between WES and WGS

WES and WGS are both NGS methods with different coverage and applications.

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Introduction

The right choice between WES and WGS depends on the clinical question.

WES

Protein-coding regions only; lower cost.

WGS

Entire genome; detects structural variants.

Which to choose?

WES is usually first-line; WGS for complex or research cases.

Frequently Asked Questions

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Gene Negar Ayandegan · Difference Between WES and WGS