Overview
Breast cancer is the most common cancer in women; a subset has a hereditary basis.
When may cancer be hereditary?
Young age at diagnosis, strong family history, bilateral cancer or male breast cancer.
Important genes
BRCA1, BRCA2, PALB2, TP53, CHEK2, ATM.
Recommended tests
BRCA1/2 and hereditary cancer panel.
Who should consider testing?
Patients with family history, young onset, bilateral disease or triple-negative tumors.
Benefits for family members
Targeted testing for relatives and early screening programs.