Cancer Genetics

Ovarian Cancer Genetics

A meaningful fraction of epithelial ovarian cancers have hereditary causes.

Cancer Genetics

Overview

Ovarian cancer has a relatively high proportion of hereditary cases among women's cancers.

When is it hereditary?

Young age, family history of breast/ovarian cancer, Lynch syndrome.

Important genes

BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, MLH1, MSH2.

Recommended tests

BRCA1/2 and hereditary cancer panel.

Who should be tested?

All patients with epithelial ovarian cancer.

Benefits for family members

Risk assessment and preventive options including risk-reducing surgery.

Frequently Asked Questions

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Contact Gene Negar Ayandegan for sample submission, laboratory collaboration, or more information.

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