Overview
Ovarian cancer has a relatively high proportion of hereditary cases among women's cancers.
When is it hereditary?
Young age, family history of breast/ovarian cancer, Lynch syndrome.
Important genes
BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, MLH1, MSH2.
Recommended tests
BRCA1/2 and hereditary cancer panel.
Who should be tested?
All patients with epithelial ovarian cancer.
Benefits for family members
Risk assessment and preventive options including risk-reducing surgery.