How does this differ from an NGS cancer panel?

Hereditary panels test germline DNA for inherited risk; somatic panels study the tumor itself.

Should family members also be tested?

If a pathogenic variant is found, targeted cascade testing is recommended for first-degree relatives.

No, it indicates increased risk rather than certainty.

Genetic Tests

Hereditary cancer panels evaluate high- and moderate-penetrance genes linked to inherited cancer syndromes.

Simultaneous analysis of dozens of genes linked to hereditary cancers such as BRCA1/2, TP53, PTEN, APC and Lynch syndrome genes.

For individuals with family history of cancer, early-onset disease, multiple primaries or rare cancers.

EDTA whole blood or saliva.

BRCA1, BRCA2, TP53, PTEN, STK11, CDH1, MLH1, MSH2, MSH6, PMS2, APC, MUTYH and others.

Identification of inherited pathogenic variants supporting personal and family risk management.

VUS interpretation requires clinical follow-up and a negative result does not exclude all risk.

To Be Added

To Be Added

Breast, ovarian, colorectal, prostate, pancreatic cancers and syndromes such as Lynch syndrome.

Contact Gene Negar Ayandegan for sample submission, laboratory collaboration, or more information.